I've been running backups awhile now - nothing unusual - UrBackup on the UNRAID server to backup my desktop and its (seven?) volumes, and TimeMachine (also on the UNRAID server) to backup my Minis and (more importantly) the MacBook Pro - which is only connected to TimeMachine when I am on my personal VPN which allows me to connect to the UNRAID shares at home (and subsequent Windows shares through UNRAID) when I am away, which these days is more often than not. Given the storage capacity of the MacBook, I do most of my audio/video (but not AI) work on the UNRAID shares over VPN, which translates into TimeMachine not being able to assist much in that regard as it doesn't cover remote-mounted volumes (though it does cover the USB-attached volume).
I was working on the graphic below, which contains less than 20 layers, and was saving the PSD file frequently. During one of my last saves I received a "disk error" message, so saved it again - that one went through - then closed the file. As it turns out, the save wasn't successful and I was unable to open it later. I tried a variety of tools which were supposed to work, but didn't, before I remembered I had backups. I logged into the UrBackup GUI (located on the UNRAID server), selected the approximate time of the last known good backup (I've since changed it to two days worth of hourly incremental), and successfully restored my layered PSD. First chance I've had to test my restores, and I was thrilled it was so smooth and easy!
